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Objective:To summarize the clinical and high resolution CT(HRCT) characteristics of 141 patients with COVID-19.Methods:From January 20 to 28, 2020, 141 COVID-19 patients, 77 males and 64 females, with a median age of 49 (9, 87), were enrolled in the study. The clinical features, laboratory test results and HRCT findings of all patients were analyzed retrospectively.Results:In all of the patients, the decreasing leukocyte countin 38 (26.95%) and lymphocyte ratio in 71 (50.35%), a fever over 37.5 ℃ in 139 (98.58%), coughing in 106 (75.18%), headache in 11 (7.80%), expectoration in 41 (29.08%), chest distress in 93 (65.96%), and diarrhea in 4 (2.84%) were found. The HRCT of all patients were abnormal, including ground glass opacity (GGO) with patchy opacity in 52 (36.88%) mainly distributed along subpleural area, GGO with focal consolidation in 23 (16.31%),small patchy opacity in 27 (19.15%),large patchy consolidation in 20 (14.18%),thickened bronchovascular bundleing and blood vessel crossing the lesion in 48 (34.04%), air bronchus sign in 5 (3.55%), small nodule in 7 (4.96%),fibrous stripes and reticular opacities in 5 (3.55%), bilateral pleural effusion in 7 (4.96%), and mediastinal or bilateral hilar lymphadenopathy in 4 (2.84%).Conclusions:The clinical and HRCT manifestations of COVID-19 are various. Under the specific epidemiological background of COVID-19, chest HRCT scan should be carried out as soon as possible for early warning of this disease.
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Objective@#To summarize the clinical characteristics of 141 patients with novel coronavirus pneumonia (NCP) and the imaging characteristics of High Resolution CT(HRCT) in the chest.@*Methods@#From January 20, 2020 to 28, 141 NCP patients, 77 males and 64 females, with a median age of 49 (9,87), were retrospectively analyzed. The clinical features, laboratory examination indexes and HRCT findings of 141 NCP patients were analyzed.@*Results@#In 141 NCP patients, 38 (26.95%) had a decrease in leukocyte count and 71 (50.35%) had a decrease in lymphocyte ratio. Among 141 NCP patients, 139 (98.58%) had fever (over 37.5 ° C), 106 (75.18%) coughed, 11 (7.80%) had headache, 41 (29.08%) coughed up sputum, 93 (65.96%) had chest distress, and 4 (2.84%) had diarrhea. HRCT of 141 NCP patients were abnormal, 52 (36.88%) showed ground glass shadow (GGO) and patchy shadow, mainly subpleural distribution; 23 (16.31%) showed GGO with focal consolidation; 27 (19.15%) had small patchy blur; 20 (14.18%) had large patchy consolidation; 48 (34.04%) had bronchovascular bundle thickening and vascular perforator sign; 5 (3.55%) had Air bronchus sign; small nodule shadow in 7 cases (4.96%); fibrosis, grid shadow or strip shadow in 5 cases (3.55%); bilateral pleural effusion in 7 cases (4.96%); mediastinal or bilateral hilar lymphadenopathy in 4 cases (2.84%).@*Conclusions@#The clinical features and HRCT images of NCP are various. Under the specific epidemiological background of NCP, HRCT scan of chest should be carried out in time to make early warning of disease.
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Objective To analyze the changes of metabolites in the left posterior cingulate cortex (PCC)in patients with type 2 diabetes mellitus (T2DM),diabetic encephalopathy(DE)and healthy control(HC),to discuss the pathogenesis and to provide the biological information for the early diagnosis of DE.Methods 46 patients with clinical diagnosis of T2DM and 26 matched HC were received single-voxel MRS on the left PCC using Siemens Verio 3.0T MR scanner.Participants were divided into two groups based on MoCA scoring criteria and diabetic retinopathy,including DM group (n=31)and DE group (n=15).All T2DM patients were received fasting blood glucose,glycated hemoglobin (HbAlc)and other clinical labortory tests before MR scans.SPSS 21.0 software package was used for statistical analysis.Results (1)Ins and Ins/Cr were increased gradually in DE compared with HC and DM groups(P＜0.05).(2) NAA/Ins ratio in DE group was significant lower than that in DM and HC group,but no significant difference was observed between DM and DE groups(P＞0.05).No significant differences exsited in NAA/Cr among these three groups(P＞0.05).Conclusion MRS can be more sensitive to detect DE patients on the left PCC-related metabolic abnormalities and help DE with early screening and preliminary clinical diagnosis.The increase Ins/Cr in the left PCC area is more sensitive to the brain injury of T2DM and can refelect the progress degree.It is necessary to expand the sample size to verify its diagnostic efficacy and early warning of the brain injury.